Ácido hialurônico: uma revisão sobre a influência do peso molecular na hidratação e integridade da barreira cutânea
DOI:
https://doi.org/10.24933/e-usf.v9i1.478Palabras clave:
Ácido hialurónico. Peso molecular. Mecanismo de hidratación.Resumen
El ácido hialurónico (AH) se utiliza ampliamente en formulaciones cosméticas y dermatológicas debido a sus propiedades higroscópicas y su capacidad para modular la hidratación de la piel. Este estudio tuvo como objetivo realizar una revisión narrativa sobre los mecanismos de hidratación del AH, con énfasis en sus interacciones con la piel y sus efectos sobre la función de la barrera cutánea. El análisis de estudios recientes demostró que el AH puede atraer y retener moléculas de agua, mejorando la textura de la piel, su suavidad y reduciendo las arrugas. Se observó que el AH de alto peso molecular actúa predominantemente en la hidratación superficial, mientras que el AH de bajo peso molecular penetra en capas más profundas, contribuyendo a efectos regenerativos y sostenidos en la matriz dérmica. Además, la hidratación inducida por el AH se asoció con la restauración de la integridad de la barrera cutánea. Se concluye que el AH es un ingrediente activo eficaz en la prevención y tratamiento de la deshidratación y el envejecimiento cutáneo, con beneficios que dependen de su forma de aplicación y características moleculares.
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